Comparisons between several Nucleic Acid Dyes
|
AvanSafe
|
EtBr
|
GelRed
|
SYBR Green I
|
Sensitivity
|
High
|
High
|
High
|
Extremely High
|
Safety
|
Non-toxic
|
High toxicity & carcinogenicity
|
Non-toxic
|
Low-toxicity
|
Stability
|
High
|
High
|
High
|
Low
|
Applicability
|
Well stain dsDNA, ssDNA & RNA
|
Well stain dsDNA, worse to stain ssDNA & RNA
|
Well stain dsDNA, ssDNA & RNA
|
Well stain dsDNA finely, worse to stain ssDNA & RNA
|
Effect on DNA migration
|
Less
|
Less
|
Bigger
|
Less
|
Detection
|
UV & Blue light
|
UV & Blue light
|
UV
|
UV & Blue light
|
Price
|
fair
|
low
|
high
|
low
|